Portable Medium Exchange System

Automates culture medium replacement at low cost!

Suitable for applications where constant and frequent medium replacement is needed (e.g. iPS cell culture)

1500,- €

now 1290,- €

* All prices are net, plus VAT and shipping


automatic exchange

Automatic medium replacement

The culture medium is replaced automatically at a specified interval (3, 6, 12, or 24 hours).

Usage in Incubator Portable Medium Exchange System

Can be used in an incubator

The system can operate continuously for up to 7 days with batteries, and be placed in an incubator without any wiring.

6-well plate Portable Medium Exchange System

Accommodates a standard 6-well plate

A standard 6-well plate can be used, which reduces running cost and minimizes environmental changes resulting from introducing the system.

Microscope Portable Medium Exchange System

Observable on a microscope

The 6-well plate can remain in the system and be placed on a microscope stage when you observe the cells, which also reduces environmental changes.

Spare parts Portable Medium Exchange System


All system components that are exposed to the medium can be replaced.

Application Examples

Day 1-4 Portable Medium Exchange System

Case 1. hiPSC (human induced pluripotent stem cells)​

Colony growth was successfully observed for 4 days after passage (engraftment), during which the culture medium was automatically replaced by our system.

[Experiment Condition]

・Cells: 253G1 Human iPS cells (NHDF reprogrammed by 3 factors; Oct3/4, Sox2, Klf4)
・Feeder Cells: Mitomycin C treated SNL76/7 cells
・Medium: DMEM-12 (including KSR, NEAA, PSG, 2-ME, bFGF)

Case 2. Embryoid bodies (EB) of mouse iPS cells

iPS cells were cultured in Knockout D-MEM based myocardial differentiation medium using our system, and pulsation of differentiation-inducted cardiomyocytes derived from mouse iPS cells was observed.

Days Portable Medium Exchange System


Model NumberCEME-0102
Outer DimensionsW194×D228×H140(mm)
Product WeightApprox. 500g (Medium weight not included)
Power SupplyAA alkaline battery *2
Applicable Culture Vessel6 well plate *1
Initilally Required Medium Volume (per well)3ml *2
Volume Replaced (per well)2.7ml*2
Medium Replacement Interval3h / 6h / 12h / 24h
Wetted Part MaterialSilicone, SUS304, PP
Bottle Capacity125ml
Price1500,- € now: 1290,- €

*1 Recommened well plate: Thermo Fisher Scientific Inc.: NUNC #140675, Sumitomo Bakelite Co., Ltd. MS-80060
*2 Volume may slightly vary depending on the type of well plate.